Extensive urbanization triggers significant changes in the composition of the atmosphere and soil, which result in the change of the thermal climate and the increase of temperature in urban areas, compared to neighboring non-urban areas. The Urban Heat Island (UHI) effect is having an adverse impact on human health, which will become more intense as the duration of heatwaves is expected to increase the next years due to climate change. This was the main discussion of the LIFE ASTI project Conference, on 7 October 2019, in Thessaloniki, with the aim of informing and raising public awareness of the UHI effect, its impact on health and climate risks. Sympraxis Team participated in the Conference as one of the 6 partners of the LIFE ASTI project, which is coordinated by the Aristotle University of Thessaloniki (School of Physics, Department of Physical and Physical Applications).